Microglia are the most common immune cells in the brain, where they defend against intruders and engulf damaged neurons. Now, ...
Duke University Medical Center-led research has identified a human-specific DNA enhancer that regulates neural progenitor proliferation and cortical size. Small genetic changes in HARE5 amplify a key ...
In a new study from Karolinska Institutet, published in Nature Neuroscience, researchers have identified the neurogenic progenitor that gives rise to dopaminergic neurons, the primary neurons affected ...
A new study in zebrafish reveals that the gene nexmifb—a paralog of the human neurodevelopmental gene NEXMIF—plays a critical role in spinal motor neuron development by modulating the axon guidance ...
Neurons, the uber-connected nerve cells that act as a main switchboard for the brain, are central to some incredibly complicated processes. They make it possible to think, walk, speak, and breathe.
Dopaminergic neurons arise from progenitor cells in the ventral midbrain under the coordinated influence of morphogens such as Sonic Hedgehog, Wnt and FGF, and the action of transcription factors ...
Microglia are the most common immune cells in the brain, where they defend against intruders and engulf damaged neurons.
To better model how neurons fire and interact with glia, some scientists place the cells into a brain or grow them in an organoid. Others have produced little spheres of human neural tissue by ...
During brain development, neurons can regulate their movement until they reach their final destination thanks to a "molecular switch" involving the protein Teneurin 4 (Ten4). This protein can guide ...
A baby's neuronal development can be compromised by infections in utero Source: Peter Oslanec/Unsplash It goes without saying that the health of a pregnant mother and the conditions inside the womb ...